Addiction decreases the brain’s ability to experience natural, healthy pleasure, driving increased cravings and compulsive substance use. But can this brain deficit be healed? New research from my lab ...
Both animals and humans are motivated to seek natural rewards to feel pleasure but also avoid unpleasant and aversive stimuli that predict pain, loss and danger. Disruption of reward-related neural ...
Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal—driving ...
Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...
Scientists have found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to opioids. Our brains, even in adulthood, continually adapt to what ...
Distinct brain circuits drive two key components of addiction to the synthetic opioid drug fentanyl, according to a new finding published in Nature (2024, DOI: 10.1038/s41586-024-07440-x). The ...
Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific “anti-reward” brain circuit becomes hyperactive during withdrawal—driving ...
Researchers carrying out functional magnetic resonance imaging (fMRI) studies in different areas of the human brain have discovered how cocaine addiction disrupts the dopamine neurons that govern how ...
Changing levels of the brain protein KCC2 can alter how reward associations form, reshaping the learning process that links cues to outcomes.
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