Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Back in 1942, the term epigenetics was introduced by Conrad Waddington to present a picture of cell development, one in which cells descended a hillside and followed diverging valley paths before ...

Genome remethylation is essential for mammalian development but specific reasons are unclear. Here we examined embryonic stem (ES) cell fate in the absence of de novo DNA methyltransferases. We ...

Global DNA-methylation is affected in G- cells. Global methylation level analysis in G− and G+ condition. (A) Bart chart representing the methylation level of individual sample (y-axis, 1 = 100%) in ...

In a recent study published in the journal Molecular Psychiatry, a team of researchers conducted a large-scale meta-analysis consisting of an epigenome-wide association study to understand whether ...

WASHINGTON, D.C.—African-American men are at higher risk for prostate cancer than white men, a disparity that may be due at least in part to a gene that is reprogrammed by excessive exposure to ...

Can reprogramming our genes make us young again? A breakthrough in longevity research may be nearing its first human trials.