What appears to be “high performance” often reflects a reward system running on fumes rather than sustainable focus.

Background Understanding the dynamic neural mechanisms of sleep-wake cycles is a major challenge in sleep science and neuroengineering. Sleep, essential for maintaining brain homeostasis and cognitive ...

A research team led by McGill University has taken a close look at a long-standing idea about Parkinson’s disease and found ...

Both simple and complex aspects of behaviour are strongly linked to body energy levels. In recent years, it became clear that this link extends beyond the obvious effects of changes in fuel ...

Habits can feel mysterious, arriving almost overnight or refusing to stick despite weeks of effort. New work on a “hidden ...

Rather than thinking that adolescence ends at 18, groundbreaking brain research has shown that critical brain developmental ...

Dopamine is an important neurotransmitter that helps regulate muscle movement and promotes an emotional sense of contentment. Natural ways to increase your dopamine include eating a balanced diet, ...

A shift in a single brain protein can reshape how cues turn into habits, opening new possibilities for treating addiction and neurological disorders.

Summary: Changing levels of the brain protein KCC2 can alter how reward associations form, reshaping the learning process that links cues to outcomes. Reduced KCC2 activity increased dopamine neuron ...

This article proposes that ibogaine’s induction of GDNF, modulation of glutamate and dopamine signaling, and reopening of plasticity represent a unified mechanism capable of restoring reward system ...